PhosLo

What is PhosLo?

PhosLoPhosLo is a medication containing calcium acetate, primarily used to manage high phosphorus levels in patients with chronic kidney disease, especially those undergoing dialysis. As a phosphate binder, this medication works by binding to phosphorus in the digestive tract, which reduces its absorption into the bloodstream. This helps prevent hyperphosphatemia (excess phosphorus in the blood), a common issue for kidney patients that can lead to complications like bone and cardiovascular problems. The drug’s calcium acetate formula also provides a beneficial source of calcium, which supports bone health, especially when phosphorus levels are controlled effectively.

For those managing kidney disease, this product can be a crucial part of treatment. By lowering phosphorus levels, PhosLo helps to protect against bone weakness and vascular calcification, conditions that can arise from untreated hyperphosphatemia. The medication is typically taken with meals, ensuring that phosphorus from food is effectively managed. Regular monitoring of phosphorus and calcium levels is essential while using this phosphate binder, and it’s always recommended to follow a healthcare provider’s guidance on dosage and dietary considerations to optimize the benefits of this medication.

Where to Buy PhosLo

Several reputable online pharmacies offer PhosLo at affordable prices with secure checkout and dependable customer support. Below is a quick comparison of popular options, showcasing price per pill, key benefits, and customer ratings.

Pharmacy Price per Pill Key Benefits Customer Rating
Canadian Pharmacy $0.63 24/7 support, fast shipping, expert advice ★★★★★ (5.0)
Blink Health $0.57 Easy ordering, secure payments, trusted source ★★★★☆ (4.7)
HealthWarehouse $0.34 Lowest price, straightforward checkout ★★★★☆ (4.6)
MedsEngage $0.67 Reliable delivery, loyalty rewards, secure ★★★★☆ (4.5)

Each pharmacy offers unique advantages for buying generic calcium acetate online, whether you’re looking for affordability, fast delivery, or additional support. Choosing the best option depends on your budget and service needs.

FAQ

What is the drug PhosLo used for?

PhosLo (calcium acetate) is used to control high phosphate levels in individuals with chronic kidney disease (CKD), especially those undergoing dialysis. When the kidneys are unable to effectively filter out excess phosphate, it can build up in the bloodstream, causing complications like weakened bones and vascular calcification. The drug works by binding to dietary phosphate in the digestive tract, preventing its absorption into the bloodstream and helping to maintain safer phosphate levels.

Calcium acetate tablets help reduce blood phosphate levels, protecting CKD patients from phosphate buildup. By supporting bone health, it helps prevent the weakening effects high phosphate levels can have on bones. Additionally, this tablet minimizes cardiovascular risks by reducing the likelihood of vascular calcification, a common issue in CKD. When combined with a low-phosphate diet, the drug is even more effective and is easy to take with meals, maximizing its phosphate-binding effects. Through these actions, this dialysis phosphate binder plays a vital role in supporting the overall health of CKD patients, reducing risks associated with elevated phosphate levels.

How does it work in the body to control phosphate levels?

PhosLo works by binding to dietary phosphate in the stomach, reducing the amount absorbed into the bloodstream. This action helps manage serum phosphate levels, especially for people with kidney disease who can’t filter excess phosphate. As the bound phosphate is removed through the digestive system, it minimizes phosphate buildup in the blood, which can lead to complications like bone disease and vascular calcification. This ckd phosphate control medication, containing calcium acetate, dissolves in the stomach acid, making it effective in binding phosphate before it can be absorbed. The body then excretes the bound phosphate naturally. By controlling phosphate levels, the drug supports better mineral balance and protects against further complications associated with high phosphate. Regular use, as prescribed, is essential for it to be effective. Consulting a healthcare provider for dosage adjustments can help optimize its benefits.

What should you not take with PhosLo?

Certain medications and supplements should not be taken with this calcium-based phosphate binder due to potential interactions. Here are some examples:

  • Antibiotics like tetracyclines and fluoroquinolones, as calcium acetate may reduce their absorption and effectiveness.
  • Thyroid medications – The dietary phosphate binder can interfere with the absorption of thyroid hormones, making them less effective.
  • Calcium and vitamin D supplements – These increase the risk of hypercalcemia when combined with PhosLo.
  • Diuretics such as hydrochlorothiazide, which may elevate calcium levels further.

It’s essential to inform your healthcare provider about all medications and supplements you’re taking to avoid interactions and maintain safe treatment with phosphate control medication.

What are the potential side effects of taking PhosLo?

PhosLo (calcium acetate) is effective in managing phosphate levels, but it can cause side effects, especially with prolonged use or high doses. Knowing the possible side effects and their frequency can help patients monitor their response to the medication and seek medical advice if necessary. Here is an overview of the potential side effects and their approximate occurrence:

  • Nausea – mild to moderate stomach discomfort (15-20%)
  • Constipation – slowing of digestion, leading to difficulty with bowel movements (5-10%)
  • Stomach Upset – bloating or abdominal discomfort after taking the phosphorus-lowering drug (10-15%)
  • Hypercalcemia (High Calcium Levels) – can cause symptoms like fatigue, muscle weakness, and confusion, particularly with high doses (1-5%)
  • Allergic Reactions – rare cases of skin reactions such as rash, itching, or swelling, especially around the face and throat (<1%)

It’s important to drink plenty of water, follow dietary recommendations, and attend regular follow-up appointments to monitor for any side effects. If unusual symptoms appear, patients should contact their healthcare provider to adjust their dosage or consider alternative treatments if needed.

What is another name for PhosLo?

PhosLo is also known by its generic name, calcium acetate. Some patients may find it listed or prescribed under this name, as calcium acetate is the active ingredient responsible for its phosphate-binding properties. Calcium acetate is commonly used in both generic and brand-name formulations to manage high phosphate levels in individuals with chronic kidney disease (CKD). Both names refer to the same medication, and they function identically to bind dietary phosphate in the digestive tract. If patients see “calcium acetate” on their prescription, they can be assured it provides the same phosphate-binding benefits.

Can PhosLo cause hypercalcemia?

Yes, PhosLo can lead to hypercalcemia, or elevated calcium levels in the blood, especially in patients taking high doses or those with other calcium sources in their diet. Hypercalcemia is a recognized side effect of calcium-based phosphate binders, as noted by a study published in the Journal of Renal Nutrition (2019), which found that about 10-20% of patients on calcium acetate experienced elevated calcium levels requiring monitoring and adjustment. The National Kidney Foundation (NKF) advises that patients on calcium-based phosphate binders should have their blood calcium levels checked frequently, as hypercalcemia can lead to complications such as fatigue, muscle weakness, and cardiovascular issues.

In 2020, a clinical review in Kidney Medicine emphasized that calcium-based binders, including PhosLo, should be used carefully, especially in patients with advanced chronic kidney disease, as studies suggest they may contribute to vascular calcification if hypercalcemia is not managed. For this reason, the NKF recommends that calcium-based binders can be used under close supervision and that alternative binders may be considered if hypercalcemia persists.

Does PhosLo cause constipation?

Yes, constipation is a known side effect of PhosLo for some users. As a calcium acetate-based medication, it can slow down the digestive tract, which may lead to issues like constipation, bloating, and stomach discomfort. Studies have shown that 5-10% of patients on calcium-based phosphate binders like this one report constipation. Drinking plenty of water and maintaining a balanced diet rich in fiber can help alleviate these symptoms. Patients who experience significant discomfort should consult their healthcare provider, as adjusting the dosage or exploring alternative phosphate binders may be necessary. Regular follow-ups and monitoring can help manage and mitigate these digestive side effects effectively.

When do you give PhosLo?

PhosLo is typically given with meals to maximize its phosphate-binding effect. Taking it during meals ensures the medication can effectively bind to dietary phosphate, reducing the amount absorbed into the bloodstream. This is especially beneficial for individuals with chronic kidney disease (CKD) or those on dialysis, who cannot naturally filter out excess phosphate. The drug’s effectiveness depends on consistent timing with food and following the prescribed dosage to avoid complications.

Key Guidelines for Taking PhosLo:

  • Take with meals – Allows the tablet to bind phosphate from food.
  • Do not crush or chew tablets – Swallow whole for full effectiveness.
  • Follow prescribed dosage – Adhering to the doctor’s instructions is essential.
  • Low-phosphate diet – Pairing the tablet with a diet low in phosphate (e.g., reducing dairy, meat, and processed foods) can enhance its benefits.
  • Regular blood tests – Monitoring helps adjust dosage and track calcium levels.

Following these guidelines ensures your phosphate control medication works effectively to control phosphate levels, helping manage CKD-related complications.

Why take PhosLo with meals?

Taking the tablet with meals enhances its phosphate-binding ability, allowing it to work effectively by binding to dietary phosphate as it enters the stomach. This timing is critical because PhosLo’s purpose is to prevent phosphate from being absorbed into the bloodstream, reducing phosphate levels in patients with chronic kidney disease (CKD). By binding with food-bound phosphate, calcium acetate helps manage serum phosphate levels, minimizing the risk of bone and vascular complications. Consistent timing with meals ensures optimal results, and following a low-phosphate diet can further improve its effectiveness. Patients are advised to take the product as prescribed and adhere to these meal-based guidelines to achieve the best outcomes.

Who should not take PhosLo?

This hyperphosphatemia treatment is generally effective for managing phosphate levels, but certain individuals may need to avoid it due to health risks. Consulting a healthcare provider is crucial to determine if the drug is the right fit for you. Here are some cases where PhosLo might not be suitable:

  • Individuals with hypercalcemia – If you already have high calcium levels, calcium acetate can elevate them further.
  • Those with a history of calcium-based kidney stones – The dialysis phosphate binder may increase calcium, which could worsen this condition.
  • People with low phosphate levels (hypophosphatemia) – Since hyperphosphatemia treatment reduces phosphate, it may not be suitable.
  • Pregnant or breastfeeding women – Should only take calcium acetate if advised by a healthcare provider.
  • Patients on medications like digitalis – Some drugs, like digitalis for heart conditions, may interact negatively with calcium acetate.

Always discuss your medical history and current medications with your doctor to ensure the drug is safe for you.

Why do people take PhosLo?

People take this phosphorus-lowering drug to control high phosphate levels, primarily in cases of chronic kidney disease (CKD) where the kidneys cannot filter out excess phosphate. Elevated phosphate levels can lead to serious complications, including weakened bones and vascular calcification. By binding to dietary phosphate, the medication helps reduce its absorption into the bloodstream, protecting CKD patients from these health risks. Patients on dialysis especially benefit from this phosphate absorption blocker, as it aids in managing mineral balance and reducing complications associated with high phosphate. This phosphate binder is usually prescribed as part of a comprehensive treatment plan that includes dietary changes and regular monitoring of phosphate and calcium levels.

Can it interact with other medications or supplements?

PhosLo can interact with certain medications and supplements, which may reduce its effectiveness or cause adverse effects. It’s important to tell your doctor about all medications you’re taking to prevent unwanted interactions. Here are some key examples:

  • Antibiotics (e.g., tetracyclines, fluoroquinolones) – Calcium acetate can bind to these drugs, lowering their absorption and effectiveness.
  • Thyroid medications – This hyperphosphatemia treatment may reduce the absorption of thyroid medications, impacting their efficacy.
  • Calcium and vitamin D supplements – These can increase the risk of hypercalcemia when taken with the phosphate binder.
  • Diuretics like hydrochlorothiazide – Certain diuretics may raise calcium levels, adding potential risk if used with calcium acetate.

Always consult your healthcare provider before combining calcium acetate tablets with other medications or supplements to ensure a safe treatment plan.

What lifestyle changes support the effectiveness of this drug?

Adopting lifestyle changes can boost PhosLo’s effectiveness and help you manage phosphate levels more efficiently. Integrating the following practices can complement your treatment:

  • Follow a low-phosphate diet – Limit high-phosphate foods like dairy, red meat, and processed foods for better phosphate control.
  • Incorporate regular exercise – Staying active supports overall health and can aid in treatment.
  • Stay hydrated – Drinking plenty of water can alleviate side effects like constipation.
  • Track your calcium and phosphate intake – Monitoring intake helps you follow dietary guidelines effectively.
  • Attend regular check-ups – Routine lab work ensures your calcium and phosphate levels remain balanced and helps adjust dosages if necessary.

These lifestyle adjustments, alongside calcium acetate pills, offer a well-rounded approach to managing high phosphate levels effectively.


Disclaimer: The information provided on this website is intended solely for educational purposes and should not replace professional medical advice, diagnosis, or treatment. For any health concerns or questions about treatment options, please consult your doctor or a qualified healthcare provider for tailored guidance. Avoid delaying or disregarding medical advice based on what you read here. For urgent issues, contact your doctor or emergency services promptly. By using this site, you understand that any actions or decisions made based on its content are solely your responsibility.


Written by Marco Taglietti, M.D.
Medically Reviewed by Gopa Green, MD, FASN (Nephrologist)
Last Update on November 6, 2024